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Kreycik had almost everything on his side when he went running on that hot day: he was extremely fit, relatively young and was an experienced runner.

While some people are more vulnerable to heat than others, including the very old and young, no one is immune — not even the world’s top athletes. Many are expressing anxiety as temperatures are forecast to soar past 95 degrees this week in Paris, as the Olympic Games get underway.
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Scientists are still trying to unravel the many ways heat attacks the body. One way they do this is with environmental chambers: rooms where they can test human response to a huge range of temperature and humidity.

CNN visited one such chamber at the University of South Wales in the UK to experience how heat kills, but in a safe and controlled environment.

“We’ll warm you up and things will slowly start to unravel,” warned Damian Bailey, a physiology and biochemistry professor at the university. Bailey uses a plethora of instruments to track vital signs — heart rate, brain blood flow and skin temperature — while subjects are at rest or doing light exercise on a bike.

The room starts at a comfortable 73 degrees Fahrenheit but ramps up to 104. Then scientists hit their subjects with extreme humidity, shooting from a dry 20% to an oppressive 85%.

“That’s the killer,” Bailey said, “it’s the humidity you cannot acclimatize to.”

And that’s when things get tough.

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Eugenewon Mon, 26 Aug 2024 09:00:47

Tiny shards of plastic are increasingly infiltrating our brains, study says
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Human brain samples collected at autopsy in early 2024 contained more tiny shards of plastic than samples collected eight years prior, according to a preprint posted online in May. A preprint is a study which has not yet been peer-reviewed and published in a journal.

“The concentrations we saw in the brain tissue of normal individuals, who had an average age of around 45 or 50 years old, were 4,800 micrograms per gram, or 0.5% by weight,” said lead study author Matthew Campen, a regents’ professor of pharmaceutical sciences at the University of New Mexico in Albuquerque.
“Compared to autopsy brain samples from 2016, that’s about 50% higher,” Campen said. “That would mean that our brains today are 99.5% brain and the rest is plastic.”

That increase, however, only shows exposure and does not provide information about brain damage, said Phoebe Stapleton, an associate professor of pharmacology and toxicology at Rutgers University in Piscataway, New Jersey, who was not involved in the preprint.

“It is unclear if, in life, these particles are fluid, entering and leaving the brain, or if they collect in neurological tissues and promote disease,” she said in an email. “Further research is needed to understand how the particles may be interacting with the cells and if this has a toxicological consequence.”

The brain samples contained 7% to 30% more tiny shards of plastic than samples from the cadavers’ kidneys and liver, according to the preprint.

“Studies have found these plastics in the human heart, the great blood vessels, the lungs, the liver, the testes, the gastrointestinal tract and the placenta,” said pediatrician and biology professor Dr. Philip Landrigan, director of the Program for Global Public Health and the Common Good and the Global Observatory on Planetary Health at Boston College.

“It’s important not to scare the hell out of people, because the science in this space is still evolving, and nobody in the year 2024 is going to live without plastic,” said Landrigan, who was not involved with the preprint.

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